Dorking
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Background Information Variants Annotation&Density Genetic Differentiation
Genetic Affinity ADMIXTURE Analysis Runs of Homozygosity
Linkage Disequilibrium Decay Demographic History Selection

Background Information

Breed Card
Breed Dorking
Species taxonomy Gallus gallus domesticus
Classification Traditional
Region England
Purpose Broiler
Description

The Dorking is a breed of Chickens that is believed to have originated in Italy during the period of the Roman Empire. It was developed to its modern shape and traits in Great Britain and got named after the town of Dorking in England. The Standard of Excellence in Exhibition Poultry included the Dorking in its first poultry standard in its publication in 1865. Interest in this chicken breed rapidly decreased during the Second World War. As of 2007, this chicken breed is included in the list of endangered- maintained species.

Characteristics

The Dorking has a rectangular body shape with very short, five-toed yellowish-white legs. They are also well-known for their versatility as a breed for both egg and meat production. The Dorking has red earlobes and two types of combs depending on the color-variety; single in red and silver-duckwing, rose in cuckoo and white, and single or rose in dark. The hens are good layers of creamy white eggs (around 150 - 200 eggs per year) and most of them go broody too. The roosters weigh 4.5 - 5.9 kg; then hens weigh 3.6 - 5 kg.


Samples Information

Variants Annotation&Density

Annotation Population SNP Total SNP Percentage SNP Population INDEL Total INDEL Percentage INDEL
downstream 121887 650455 18.7387% 11318 104154 10.8666%
exonic;splicing 25 188 13.2979% 0 0 0%
exonic_unknown 25 582 4.2955% 0 82 0%
frameshift_deletion 0 0 0% 708 15977 4.4314%
frameshift_insertion 0 0 0% 611 13308 4.5912%
intergenic 2808109 15129055 18.561% 235621 2238383 10.5264%
intronic 3489812 17735594 19.6769% 305590 2641780 11.5676%
ncRNA_exonic 72687 400185 18.1633% 5614 54342 10.3309%
ncRNA_exonic;splicing 55 231 23.8095% 3 43 6.9767%
ncRNA_intronic 707753 3728327 18.9831% 62876 575920 10.9175%
ncRNA_splicing 414 2341 17.6848% 61 478 12.7615%
ncRNA_UTR5 0 0 0% 1 18 5.5556%
nonframeshift_deletion 0 0 0% 418 8777 4.7624%
nonframeshift_insertion 0 0 0% 186 4784 3.888%
nonsynonymous 31376 336233 9.3316% 0 0 0%
splice_acceptor 69 750 9.2% 60 964 6.2241%
splice_donor 76 1076 7.0632% 24 763 3.1455%
splice_donor_acceptor 0 0 0% 14 45 31.1111%
splice_UTR5 56 400 14% 6 106 5.6604%
splie_Others 0 0 0% 35 654 5.3517%
startloss 103 671 15.3502% 3 51 5.8824%
stopgain 348 4175 8.3353% 24 1252 1.9169%
stoploss 59 353 16.7139% 6 63 9.5238%
synonymous 73827 548813 13.4521% 0 0 0%
upstream 124764 679592 18.3587% 10054 98760 10.1802%
upstream;downstream 10333 57451 17.9858% 941 9367 10.0459%
UTR3 60325 361040 16.7087% 6446 61415 10.4958%
UTR5 17060 112990 15.0987% 1264 16935 7.4638%
UTR5;UTR3 396 2524 15.6894% 39 381 10.2362%
Total 7519559 39753026 18.9157% 641923 5848802 10.9753%
SNP Density
SNP_Annotation
INDEL Density
INDEL_Annotation

Genetic Differentiation

Summary

Genetic affinities of target population in the context of worldwide populations are measured by pairwise FST between target population and references. Smaller FST value indicates closer relationship. Regions represented by different colors are indicated above.

Genetic Affinity

PCA for G.gallus without G.g.bankiva , G.g.jabouillei, and some G.g.gallus

Summary

Genetic affiliation and population structure are shown by PCA plots. After removing G. g. bankiva, G. g. jabouillei, and some G. g. gallus individuals as outliers to other Red Jungle Fowl, the dataset contains 1,915 samples from domestic chicken and Red Jungle Fowl. User can add any populations with interests to show with the target population under this PCA context by using the item of “Add”.

ADMIXTURE Analysis

Summary

The inference of populations and individual ancestries is revealed by ADMIXTURE clustering. Length of each colored bar represents the proportion of proposed ancestry in the sample. User can add any populations with interests to compare with the target population by using the item of “Add”. The number of proposed ancestries is determined by “which K”.

Runs of Homozygosity

Summary

Runs of homozygosity (ROH) indicates long tracts of homozygous genotypes inherited from identical haplotypes of a common ancestor. Larger populations have fewer, shorter ROH, whereas isolated or bottlenecked populations have more, somewhat longer ROH. Admixture brings the fewest ROH, whereas inbreeding causes long ROH. The level of ROH is measured by number and length. The length of ROH can be defined in “ROH range”. User can add any populations with interests to compare with the target population by using the item of “Add”.

Linkage Disequilibrium Decay

Summary

Linkage disequilibrium (LD) decay is characterized by squared correlations (r²) of all SNPs frequencies against the physical distances between SNPs. User can add any populations with interests to compare with the target population by using the item of “Add”.

Demographic History

Summary

The changes of effective population size through time is inferred by SMC++. User can add any populations with interests to compare with the target population by using the item of “Add”.

Selection

Summary

Selective signals of the target population are detected by different methods. X axis indicates physical position of specific chromosomal region with interests which can be defined by “Region”. The gene annotation is shown below. Y axis of left (YL) indicates the values of Pi-ratio of -log2(πRJF/πTarget) or composite likelihood ratio (CLR) of SweeD. The levels of statistical significance are noted with different colors. Y axis of right (YR) shows the values of Fst (Target vs. Red Jungle Fowl), Pi, or Tajima’s D with blue line with sliding window approach. The genomic window size and step size for Tajima’s D are 5 kb and 5 kb, respectively. The genomic window size and step size for Fst and Pi are 10 kb and 5 kb, respectively. The methods are defined by “Method-YL” and “Method-YR”.

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