Cochin
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Background Information Variants Annotation&Density Genetic Differentiation
Genetic Affinity ADMIXTURE Analysis Runs of Homozygosity
Linkage Disequilibrium Decay Demographic History Selection

Background Information

Breed Card
Breed Cochin
Species taxonomy Gallus gallus domesticus
Classification Commercial
Region England
Purpose Fancy
Description

The Cochin is a breed of large domestic chicken. It derives from large feather-legged chickens brought from China to Europe and North America during 1840s and 1850s. It is reared principally for exhibition and pet. It was formerly known as Cochin-China.

Characteristics

The Cochin breed was developing in China mainly for the large size broiler. This breed has single comb. The roosters have 11 lbs and hens have 9 lbs in weight. Another notable feature is the bird's plentiful feathering, that covers not only the body but its legs and feet, making an already large bird appear even larger. It comes in a wide variety of colors and patterns. The hens are broody.


Samples Information

Variants Annotation&Density

Annotation Population SNP Total SNP Percentage SNP Population INDEL Total INDEL Percentage INDEL
downstream 117951 650455 18.1336% 10795 104154 10.3645%
exonic;splicing 29 188 15.4255% 0 0 0%
exonic_unknown 21 582 3.6082% 0 82 0%
frameshift_deletion 0 0 0% 676 15977 4.2311%
frameshift_insertion 0 0 0% 582 13308 4.3733%
intergenic 2706068 15129055 17.8866% 223248 2238383 9.9736%
intronic 3371259 17735594 19.0084% 291646 2641780 11.0398%
ncRNA_exonic 70332 400185 17.5749% 5362 54342 9.8671%
ncRNA_exonic;splicing 59 231 25.5411% 6 43 13.9535%
ncRNA_intronic 680293 3728327 18.2466% 59533 575920 10.337%
ncRNA_splicing 416 2341 17.7702% 46 478 9.6234%
ncRNA_UTR5 0 0 0% 0 18 0%
nonframeshift_deletion 0 0 0% 345 8777 3.9307%
nonframeshift_insertion 0 0 0% 206 4784 4.306%
nonsynonymous 30406 336233 9.0431% 0 0 0%
splice_acceptor 55 750 7.3333% 64 964 6.639%
splice_donor 80 1076 7.4349% 29 763 3.8008%
splice_donor_acceptor 0 0 0% 11 45 24.4444%
splice_UTR5 51 400 12.75% 6 106 5.6604%
splie_Others 0 0 0% 27 654 4.1284%
startloss 95 671 14.158% 5 51 9.8039%
stopgain 341 4175 8.1677% 17 1252 1.3578%
stoploss 52 353 14.7309% 5 63 7.9365%
synonymous 71427 548813 13.0148% 0 0 0%
upstream 121950 679592 17.9446% 9676 98760 9.7975%
upstream;downstream 10168 57451 17.6986% 894 9367 9.5441%
UTR3 58954 361040 16.3289% 5936 61415 9.6654%
UTR5 16977 112990 15.0252% 1253 16935 7.3989%
UTR5;UTR3 345 2524 13.6688% 37 381 9.7113%
Total 7257329 39753026 18.256% 610405 5848802 10.4364%
SNP Density
SNP_Annotation
INDEL Density
INDEL_Annotation

Genetic Differentiation

Summary

Genetic affinities of target population in the context of worldwide populations are measured by pairwise FST between target population and references. Smaller FST value indicates closer relationship. Regions represented by different colors are indicated above.

Genetic Affinity

PCA for G.gallus without G.g.bankiva , G.g.jabouillei, and some G.g.gallus

Summary

Genetic affiliation and population structure are shown by PCA plots. After removing G. g. bankiva, G. g. jabouillei, and some G. g. gallus individuals as outliers to other Red Jungle Fowl, the dataset contains 1,915 samples from domestic chicken and Red Jungle Fowl. User can add any populations with interests to show with the target population under this PCA context by using the item of “Add”.

ADMIXTURE Analysis

Summary

The inference of populations and individual ancestries is revealed by ADMIXTURE clustering. Length of each colored bar represents the proportion of proposed ancestry in the sample. User can add any populations with interests to compare with the target population by using the item of “Add”. The number of proposed ancestries is determined by “which K”.

Runs of Homozygosity

Summary

Runs of homozygosity (ROH) indicates long tracts of homozygous genotypes inherited from identical haplotypes of a common ancestor. Larger populations have fewer, shorter ROH, whereas isolated or bottlenecked populations have more, somewhat longer ROH. Admixture brings the fewest ROH, whereas inbreeding causes long ROH. The level of ROH is measured by number and length. The length of ROH can be defined in “ROH range”. User can add any populations with interests to compare with the target population by using the item of “Add”.

Linkage Disequilibrium Decay

Summary

Linkage disequilibrium (LD) decay is characterized by squared correlations (r²) of all SNPs frequencies against the physical distances between SNPs. User can add any populations with interests to compare with the target population by using the item of “Add”.

Demographic History

Summary

The changes of effective population size through time is inferred by SMC++. User can add any populations with interests to compare with the target population by using the item of “Add”.

Selection

Summary

Selective signals of the target population are detected by different methods. X axis indicates physical position of specific chromosomal region with interests which can be defined by “Region”. The gene annotation is shown below. Y axis of left (YL) indicates the values of Pi-ratio of -log2(πRJF/πTarget) or composite likelihood ratio (CLR) of SweeD. The levels of statistical significance are noted with different colors. Y axis of right (YR) shows the values of Fst (Target vs. Red Jungle Fowl), Pi, or Tajima’s D with blue line with sliding window approach. The genomic window size and step size for Tajima’s D are 5 kb and 5 kb, respectively. The genomic window size and step size for Fst and Pi are 10 kb and 5 kb, respectively. The methods are defined by “Method-YL” and “Method-YR”.

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