White Leghorn
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Background Information Variants Annotation&Density Genetic Differentiation
Genetic Affinity ADMIXTURE Analysis Runs of Homozygosity
Linkage Disequilibrium Decay Demographic History Selection

Background Information

Breed Card
Breed White Leghorn
Species taxonomy Gallus gallus domesticus
Classification Commercial
Region Europe
Purpose Layer
Description

Leghorn chickens originate from Italy, being sent to America around 1830. It is quite often thought of as an American bird since it was refined and perfected into a stable breed in the United States before being shipped back to Europe. It arrived in the UK in 1869. The white color-variety surpasses any other Leghorn hen in its laying abilities. That led to a market advantage, and hence many strains have been developed from the white Leghorn to produce plenty of white eggs throughout the year.

Characteristics

Leghorns have white earlobes, bright-yellow legs, and large combs and wattles. The breed comes comes in two varieties; the single-combed and the less common rose-combed. Leghorn hens are prolific layers of relatively large white eggs (around 280 eggs or more per year), but they rarely go broody. The avaerage weight is 2.75 kg and 2 kg for roosters and hens, respectively.


Samples Information

Variants Annotation&Density

Annotation Population SNP Total SNP Percentage SNP Population INDEL Total INDEL Percentage INDEL
downstream 74814 650455 11.5018% 6801 104154 6.5298%
exonic;splicing 17 188 9.0426% 0 0 0%
exonic_unknown 23 582 3.9519% 0 82 0%
frameshift_deletion 0 0 0% 360 15977 2.2532%
frameshift_insertion 0 0 0% 331 13308 2.4872%
intergenic 1745914 15129055 11.5401% 146980 2238383 6.5663%
intronic 2170121 17735594 12.236% 190925 2641780 7.2271%
ncRNA_exonic 44934 400185 11.2283% 3454 54342 6.356%
ncRNA_exonic;splicing 37 231 16.0173% 5 43 11.6279%
ncRNA_intronic 437068 3728327 11.7229% 38878 575920 6.7506%
ncRNA_splicing 283 2341 12.0889% 38 478 7.9498%
ncRNA_UTR5 0 0 0% 1 18 5.5556%
nonframeshift_deletion 0 0 0% 192 8777 2.1875%
nonframeshift_insertion 0 0 0% 85 4784 1.7768%
nonsynonymous 18580 336233 5.5259% 0 0 0%
splice_acceptor 34 750 4.5333% 28 964 2.9046%
splice_donor 52 1076 4.8327% 14 763 1.8349%
splice_donor_acceptor 0 0 0% 9 45 20%
splice_UTR5 36 400 9% 1 106 0.9434%
splie_Others 0 0 0% 24 654 3.6697%
startloss 65 671 9.687% 2 51 3.9216%
stopgain 196 4175 4.6946% 11 1252 0.8786%
stoploss 35 353 9.915% 3 63 4.7619%
synonymous 43552 548813 7.9357% 0 0 0%
upstream 73538 679592 10.8209% 5752 98760 5.8242%
upstream;downstream 5979 57451 10.4071% 509 9367 5.434%
UTR3 37069 361040 10.2673% 3798 61415 6.1842%
UTR5 9426 112990 8.3423% 655 16935 3.8677%
UTR5;UTR3 212 2524 8.3994% 16 381 4.1995%
Total 4661985 39753026 11.7274% 398872 5848802 6.8197%
SNP Density
SNP_Annotation
INDEL Density
INDEL_Annotation

Genetic Differentiation

Summary

Genetic affinities of target population in the context of worldwide populations are measured by pairwise FST between target population and references. Smaller FST value indicates closer relationship. Regions represented by different colors are indicated above.

Genetic Affinity

PCA for G.gallus without G.g.bankiva , G.g.jabouillei, and some G.g.gallus

Summary

Genetic affiliation and population structure are shown by PCA plots. After removing G. g. bankiva, G. g. jabouillei, and some G. g. gallus individuals as outliers to other Red Jungle Fowl, the dataset contains 1,915 samples from domestic chicken and Red Jungle Fowl. User can add any populations with interests to show with the target population under this PCA context by using the item of “Add”.

ADMIXTURE Analysis

Summary

The inference of populations and individual ancestries is revealed by ADMIXTURE clustering. Length of each colored bar represents the proportion of proposed ancestry in the sample. User can add any populations with interests to compare with the target population by using the item of “Add”. The number of proposed ancestries is determined by “which K”.

Runs of Homozygosity

Summary

Runs of homozygosity (ROH) indicates long tracts of homozygous genotypes inherited from identical haplotypes of a common ancestor. Larger populations have fewer, shorter ROH, whereas isolated or bottlenecked populations have more, somewhat longer ROH. Admixture brings the fewest ROH, whereas inbreeding causes long ROH. The level of ROH is measured by number and length. The length of ROH can be defined in “ROH range”. User can add any populations with interests to compare with the target population by using the item of “Add”.

Linkage Disequilibrium Decay

Summary

Linkage disequilibrium (LD) decay is characterized by squared correlations (r²) of all SNPs frequencies against the physical distances between SNPs. User can add any populations with interests to compare with the target population by using the item of “Add”.

Demographic History

Summary

The changes of effective population size through time is inferred by SMC++. User can add any populations with interests to compare with the target population by using the item of “Add”.

Selection

Summary

Selective signals of the target population are detected by different methods. X axis indicates physical position of specific chromosomal region with interests which can be defined by “Region”. The gene annotation is shown below. Y axis of left (YL) indicates the values of Pi-ratio of -log2(πRJF/πTarget) or composite likelihood ratio (CLR) of SweeD. The levels of statistical significance are noted with different colors. Y axis of right (YR) shows the values of Fst (Target vs. Red Jungle Fowl), Pi, or Tajima’s D with blue line with sliding window approach. The genomic window size and step size for Tajima’s D are 5 kb and 5 kb, respectively. The genomic window size and step size for Fst and Pi are 10 kb and 5 kb, respectively. The methods are defined by “Method-YL” and “Method-YR”.

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